Objective: To compare the outcome of fine-needle aspiration and core biopsy of solid breast lesions under ultrasound guidance and to evaluate if fine-needle aspiration should be replaced by core biopsy.
The treatment paradigm of advanced non–small-cell lung carcinoma has evolved considerably owing to advances in molecular targeted therapy and the approval of two new classes of therapeutic agents, namely, epidermal growth factor receptor tyrosine-kinase inhibitors and angiogenesis inhibitors.
Recent advances in chemotherapy and chemoimmunotherapy have improved the outcomes of many lymphoma patients. However, patients with relapsed or refractory disease continue to have poor outcomes.
The incidence of follicular lymphoma, a low-grade malignant B-cell lymphoma, is increasing in most Asian populations. Follicular lymphoma is generally considered to be indolent with a life expectancy of approximately 10 to 14 years.
Chronic lymphocytic leukaemia is a disease that primarily affects the elderly and has a heterogeneous clinical course. The past decade has witnessed extensive progress in its management, owing to the generation of prognostic biological markers
Adjuvant chemotherapy for node-positive breast cancers has evolved a long way from the time-honoured nonanthracycline regimen of six cycles of CMF (cyclophosphamide, methotrexate, 5-fluorouracil) to the historical standard of anthracycline-based regimens
Colorectal cancer is one of the most frequently diagnosed malignancies in the world. In Hong Kong, colorectal cancer is the second most common cancer and accounted for 16% of all new cancer cases in 2008.
It is now well recognised that patients with metastatic colorectal cancer represent heterogeneous subgroups of patients with differing prognoses, because of differences in the number and sites of metastases, performance status, and the types of prior treatment.
Gastric carcinoma is one of the most common cancers worldwide. Patients in the early stages of the disease experience non-specific symptoms. This contributes greatly to delayed diagnoses and poor prognoses, as reflected by low survival rates.
Most patients with ovarian cancer undergo surgery at some point during the course of their treatment. A primary operation may be undertaken for the purpose of confirming the diagnosis, staging, and debulking.
Angiogenesis, or the development of micro-vascular (blood and lymph) networks from established vasculature, is a process fundamental to proliferation, invasion and metastasis of ovarian cancer and other solid tumours.
Bevacizumab is one of the novel pharmacological agents used for the treatment of multiple tumour types including metastatic colorectal cancer, non–small-cell lung cancer, metastatic breast cancer, glioblastoma multiforme, and metastatic renal carcinoma.
Multi-detector computed tomography has become a vital tool in imaging of the spleen. We present a pictorial review of multi-detector computed tomography imaging features of the normal spleen, its anatomic variants, and when it is affected by pathology.
Umbilical venous catheterization is a commonly performed bedside procedure in the neonatal unit. Potential complications include vascular perforation, thrombosis, embolism, haemorrhage, infection, and tissue injuries.
Isolated spontaneous dissection of the superior mesenteric artery is rare. Conventional treatment involves surgical or conservative management, and is increasingly supported by radiological interventions.
Intracranial cavernoma is a relatively rare condition. Cavernoma of the hypothalamus is even rarer. We report a case of hypothalamic cavernoma presenting with ptosis.
Dedifferentiated chondrosarcoma is a rare but highly malignant form of chondrosarcoma with grave prognosis. Early and accurate diagnosis followed by radical surgery seems the only treatment to improve survival.
KCH Lau, CY Lui, LMF Tee, YHA Tsang, KKT Pak, M Ying, CM Chan, HS Lam
Hong Kong J Radiol 2011;14:218-28
Objective: To determine the role of breast magnetic resonance imaging in the preoperative assessment of patients with newly diagnosed breast cancer and its impact on surgical management.
Objective: To evaluate the effectiveness and practicality of dose-reduction measures for double-contrast barium enema based on well-established UK National Reference Levels.
Objective: To improve the workflow of clinical radiological conferences held outside radiology department, where a radiology workstation is unavailable.
Baker’s cyst (Popliteal cyst) is an abnormal distension of the gastrocnemius-semimembranosus bursa, which is a commonly encountered condition in sonographic knee examinations. A cystic lesion extending between the tendons of semimembranosus
W Shi, RC Nichols, S Flampouri, W Hsi, Z Li, RH Henderson, NP Mendenhall, B Hoppe
Hong Kong J Radiol 2011;14:190-4
This study aimed to evaluate the dosimetric impact of tumour shrinkage during proton-based chemoradiotherapy. This dosimetric study describes a patient who presented with synchronous bilateral T2 non–small-cell lung cancers with no clinical or radiographical
Fibrolipomatous hamartoma is a rare condition caused by hypertrophy of mature fat and fibroblasts in the epineurium, resulting in fibrofatty infiltration and an enlarged peripheral nerve. The median nerve is most commonly affected, in which case it can be associated
Retroclival epidural haematoma is a very rare type of haematoma that occurs mainly in the paediatric agegroup, as a result of ligamentous laxity at the craniocervical junction. All previously reported cases were pedestrians or cyclists hit by a motor vehicle and
We present a case of bilateral Wilms’ tumours in a three-year-old girl. In addition, we briefly discuss the differential diagnoses of bilateral Wilms’ tumours and their further characterisation from unilateral tumours. Younger age at presentation, association of renal
Primary spinal epidural lymphoma is a rare entity and one of the differential diagnoses of an epidural spinal mass. This report describes two patients who presented with symptoms of cord compression subsequently proven to be due to primary spinal epidural lymphoma.
The combination of pulmonary artery aneurysm and intracardiac thrombus is rare in Behçet’s disease. We report on a 39-year-old man from Iraq with a clinical diagnosis of Behçet’s disease based on a nonhealing mouth ulcer, recurrent venous thromboses in both lower
Objective: The tree-in-bud sign is a common finding on thin-section computed tomography of the lungs. However, the differential diagnosis of this common radiological finding is long and exhausting. Knowledge of its common causes together with the patient’s
SSM Wong, K Wang, EHY Yuen, JKT Wong, A King, AT Ahuja
Hong Kong J Radiol 2011;14:155-60
Objective: To evaluate the value of Gallium-67 single-photon emission computed tomography/computed tomography in the diagnosis and monitoring treatment response of malignant otitis externa.
