Journal

Shifting the Paradigm for Maintenance Therapy for Non–small-cell Lung Cancer

Full Article

VHF Lee

Hong Kong J Radiol 2010;13(Suppl):S16-21

Systemic chemotherapy has been the standard treatment for advanced / metastatic non–small-cell lung cancer, particularly in those who do not harbour an epidermal growth factor receptor mutation. In the last decade, there was no established evidence to justify

Personalised Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–small-cell Lung Cancer: Consensus and Controversy

Full Article

ML Zhuo, J Wang

Hong Kong J Radiol 2010;13(Suppl):S10-5

The epidermal growth factor receptor tyrosine kinase inhibitors, including gefitinib and erlotinib, have been proven to provide significant benefit in progression-free survival and overall survival in patients who have received at least one line of prior

Current Role of Biological Agents in Colorectal Cancer

Full Article

Hong Kong J Radiol 2010;13(Suppl):S3-9

J Cassidy

Colorectal cancer is one of the most frequently diagnosed malignancies in the world. In spite of recent advances in chemotherapy, the prognosis for patients with metastatic colorectal cancer remains poor. The last decade of ground-breaking research on molecular

An Institutional Audit and Pictorial Review of Langerhans’ Cell Histiocytosis Presented with Intracranial Manifestations

Full Article

DD Rasalkar, C Tong, FWT Cheng, CK Li, BK Paunipagar, WCW Chu

Hong Kong J Radiol 2010;13:46-51

Objective: To review the intracranial manifestations and role of imaging in Langerhans’ cell histiocytosis.

Methods: This is a retrospective institutional review of clinical data and radiological findings of Langerhans’ cell histiocytosis patients

Breast Schistosomiasis Presenting as Mammographic Calcifications

Full Article

HHL Chau, APY Tang, GM Tse, TKF Ma, SK Chan

Hong Kong J Radiol 2010;13:43-5

A case of mammary schistosomiasis revealed by breast microcalcifications detected by mammography is reported. Although schistosomiasis can involve almost any organ, involvement of the breast is very rare. This case was diagnosed by stereotactic-guided

Tuberculosis of the Prostate and Seminal Vesicles

Full Article

J Joseph, H Narayanan, H Babu, A Praveen

Hong Kong J Radiol 2010;13:40-2

We report a rare manifestation of tuberculosis of the prostate and seminal vesicles without involvement of the rest of the genito-urinary tract. A 27-year-old male initially presented with clinical and laboratory evidence of pulmonary tuberculosis. Two weeks later, the

Metastatic Thyroid Carcinoma Presenting with Spinal Cord Compression

Full Article

HA Hassan, SA Hamid

Hong Kong J Radiol 2010;13:36-9

Metastatic follicular thyroid carcinoma presenting with spinal cord compression is rare. We describe a 69-yearold woman who initially presented with gradual onset of bilateral lower limb weakness and numbness for 3 months. Her magnetic resonance image revealed

Melanocytic Hyperpigmentation of the Tongue from Low-dose Radiotherapy

Full Article

RJ Amdur, PR Sandow, A Yeung, WM Mendenhall

Hong Kong J Radiol 2010;13:32-5

Several of our patients developed patches of melanotic hyperpigmentation (black spots) in the mucosa of the tongue during radiotherapy for brain tumours. The purpose of this report was to describe a representative case with a literature review. A

Segmental Pulmonary Artery Dissection in Systemic Lupus Erythematosus

Full Article

DD Rasalkar, BK Paunipagar, WCW Chu

Hong Kong J Radiol 2010;13:29-31

We report a unique case of segmental pulmonary artery dissection in a 48-year-old female, with confirmed systemic lupus erythematosus and pulmonary hypertension. Several cardiopulmonary manifestations of systemic lupus erythematosus have been

The Focal Hepatic ‘Hot Spot’ Sign of Superior Vena Cava Obstruction in Contrast-enhanced Computed Tomography

Full Article

J Joseph, H Narayanan, H Babu, A Praveen

Hong Kong J Radiol 2010;13:26-8

In patients with superior vena caval obstruction, computed tomography of the liver in its arterial or early portal phase may show abnormal hyperattenuation in segment IV of the left hepatic lobe. This abnormal enhancement is due to porto-systemic venous

Retroperitoneal Intramuscular Haemangioma: Imaging Features

Full Article

HA Hassan, SA Hamid

Hong Kong J Radiol 2010;13:23-5

Retroperitoneal intramuscular haemangiomas are quite rare. Interruption of the muscle layer by intramuscular cavernous haemangioma raised the suspicion of a soft tissue sarcoma. We discuss the radiological characteristics of a haemangioma compared to soft tissue

Retrospective Clinico-pathological Study of Germ Cell Tumours Managed in a Single Institution

Full Article

AKC Leung, KH Au, HY Yiu, YL Kwok, VC Sin, WL Leung, KC Ngan

Hong Kong J Radiol 2010;13:12-22

Objective: To study the clinico-pathological characteristics and outcome of germ cell tumours treated in the Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong.

Pre-procedure Prognostic Factors to Predict Survival of Patients after Radiofrequency Ablation of Hepatocellular Carcinoma

Full Article

WSW Chan, SS Chiu, DHY Cho, SK Kei, WL Poon, SH Luk, CC Cheung

Hong Kong J Radiol 2010;13:3-11

Objective: This study evaluated the clinical, biochemical, and imaging characteristics to identify pre-ablative prognostic factors for the survival of patients undergoing radiofrequency ablation of hepatocellular carcinoma. Radiofrequency ablation has now been

Institutional Experience of Magnetic Resonance Urography in Children: a Pictorial Essay with Literature Review

Full Article

DD Rasalkar, WCW Chu

Hong Kong J Radiol 2010;13:161-70

Conventional imaging studies such as ultrasonography, intravenous urography, micturating cystourethrography, and radionuclide scintigraphy are the basic investigations used in daily clinical practice for the diagnosis and monitoring of obstructive uropathy in

Pancreatic Neoplasm in a Patient with Situs Inversus Totalis

Full Article

BK Paunipagar, DD Rasalkar, P Lonikar, WCW Chu

Hong Kong J Radiol 2010;13:158-60

We reported on a patient with a cystic neoplasm of the pancreas with situs inversus totalis that showed the typical imaging features of serous cystadenoma in an anatomically inverted pancreas. The possible coexistence of malformations of transposed organs and

Left-sided Torsion of the Greater Omentum

Full Article

EMF Wong, SYJ Ka, WK Chau, P Tsui

Hong Kong J Radiol 2010;13:154-7

Torsion of the greater omentum is rare and is known to occur more often on the right side. We present an even rarer case of left-sided omental torsion, which was proven surgically and pathologically. Computed tomography showed the characteristic Whirl sign, which

Imaging Characteristics of Reversible Cerebral Vasoconstriction Syndrome: an Under-recognised Cause of Severe Headache

Full Article

RKL Lee, DYW Siu, AT Ahuja

Hong Kong J Radiol 2010;13:149-53

Reversible cerebral vasoconstriction syndrome is an under-diagnosed disease that every radiologist should know about. This report demonstrates two female patients who presented with severe headache with subsequent angiographic findings of ‘bead and string’

Mycotic Aneurysm of an Intercostal Artery: a Rare Cause of Haemothorax

Full Article

WP Chu, LF Cheng

Hong Kong J Radiol 2010;13:144-8

Causes of haemothorax include trauma, pulmonary or pleural neoplasm, pulmonary infarction and coagulopathy. Mycotic aneurysm of an intercostal artery is a rare cause of haemothorax. We report on a 60-year-old man who had a mycotic aneurysm of the right 12th

Brachial Artery Transection Following Closed Elbow Dislocation Without Accompanying Fracture

Full Article

YY Cheuk, KWM Yang

Hong Kong J Radiol 2010;13:140-3

Simple elbow dislocation is one of the most common joint dislocations and has a good prognosis. Complete transection of the brachial artery rarely ensues without an associated fracture. This case report describes this rare complication and its imaging findings in a

Immunoglobulin G4–related Sclerosing Disease of the Breast

Full Article

KY Kwok, HS Fung, LF Chiu, KM Chu, JCW Siu, KH Lai, TS To, SCH Chan

Hong Kong J Radiol 2010;13:137-9

Immunoglobulin G4–related sclerosing disease is a recently advocated disease entity. Though initially described as giving rise to autoimmune pancreatitis, this condition was subsequently found to involve extra-pancreatic tissues as well. In this report, we present a

Two Children with Pancreatoblastomas

Full Article

DD Rasalkar, BK Paunipagar, WCW Chu

Hong Kong J Radiol 2010;13:133-6

Pancreatoblastoma is a rare primary pancreatic neoplasm occurring in children. This report describes two paediatric patients with pancreatoblastomas with characteristic sonographic and computed tomographic features. Characteristic clinical and imaging features,

Comparison of RapidArc and Static Gantry Intensity-modulated Radiotherapy for Nasopharyngeal Carcinoma

Full Article

WK Cheung, KH Lee, HC Cheng, CH Cheung, CL Chan, KC Ngan

Hong Kong J Radiol 2010;13:125-32

Objective: RapidArc (Varian Medical Systems, Palo Alto, CA) is a new volumetric-modulated arc radiotherapy technique with continuous modulation of gantry speed, dose rate, and multileaf collimator shape. Taking advantages of dose painting capabilities

Cancer Risk of Focal Thyroid Incidentaloma in Patients Undergoing 18F-fluorodeoxyglucose Positron Emission Tomography–Computed Tomography Studies: Local Experience in a Single Centre

Full Article

BT Kung, CP Wong, KS Chu, TK AuYong, CM Tong

Hong Kong J Radiol 2010;13:120-4

Objectives: To determine the prevalence of focal thyroid fluorodeoxyglucose positron emission tomography– computed tomography incidentaloma in our locality and evaluate the rate of malignancy.

Urgent Magnetic Resonance Imaging for Malignant Spinal Cord Compression

Full Article

SSM Lo, KY Kwok, CW Siu, WK Wong, CM Chan, KW Tang, YL Cheung, SCH Chan

Hong Kong J Radiol 2010;13:111-9

Objectives: Malignant spinal cord compression is an uncommon complication in patients with cancer. It is frequently diagnosed late and causes irreversible damage to spinal cord. Malignant spinal cord compression is an oncological emergency, requiring a prompt

Imaging Features of Median Arcuate Ligament Syndrome

Full Article

SQH Chou, KY Kwok, LS Wong, DHS Fung, WK Wong

Hong Kong J Radiol 2010;13:101-3

Median arcuate ligament syndrome presents as abdominal pain. It usually occurs in young people, who presents with abdominal pain associated with eating. This pictorial review deals with 2 such patients who

Granulocytic Sarcoma with Severe Skin Involvement

Full Article

R Koul, HI Chalchal, A Dubey

Hong Kong J Radiol 2010;13:96-100

Acute myelogenous leukaemia typically involves intramedullary proliferation of myeloid precursor cells. Extramedullary manifestations of acute myelogenous leukaemia are rare. Granulocytic sarcoma, or chloroma,

Intrahepatic Cholangiocarcinoma Presenting with Spontaneous Rupture

Full Article

SYJ Ka, JLY Leung, CY Chu, AYH Wan, VWL Tang

Hong Kong J Radiol 2010;13:91-5

Spontaneous non-traumatic hepatic rupture is an uncommon condition and most often due to underlying hypervascular hepatic lesions. Cholangiocarcinomas are usually hypovascular and spontaneous rupture is

Vulval Gastrointestinal Stromal Tumours with Bone Metastases

Full Article

SQH Chou, KS Tse, WK Wong, SCH Chan

Hong Kong J Radiol 2010;13:88-90

Gastrointestinal stromal tumours are specifically diagnosed by the demonstration of a specific marker profile with the expression of c-kit and CD34. It is the most common mesenchymal tumour of the gastrointestinal

Ovarian Inguinal Hernia Complicated by Ovarian Torsion

Full Article

DD Rasalkar, BK Paunipagar, WCW Chu

Hong Kong J Radiol 2010;13:86-7

Inguinal swellings are not uncommon in infants. The differential diagnoses of inguinal masses in infants include inguinal hernia, which is one of the most frequently entertained differential diagnoses in both males

Infection in a Plexiform Neurofibroma

Full Article

N Chotai, MWC H’ng

Hong Kong J Radiol 2010;13:83-5

Plexiform neurofibroma is a typical sign of neurofibromatosis type 1, although the condition is not diagnostic. These large lesions are associated with neurological deficits, affect cosmesis, and have a predisposition for