Original Articles

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ESK Ma, CLP Wong

Hong Kong J Radiol 2010;13(Suppl):S42-50

Cancer biomarkers have evolved from assays based on proteins, hormones and enzymes to molecular assays based on DNA or RNA. These molecular cancer biomarkers have broad clinical applications in disease screening, diagnosis, classification, offering a

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RKC Ngan

Hong Kong J Radiol 2010;13(Suppl):S33-41

The GOG111 and OV-10 were pivotal studies published in 1996 and 2000 respectively which established paclitaxel / cisplatin as standard postoperative adjuvant chemotherapy for advanced epithelial ovarian cancers. A second major breakthrough in the ensuing

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J Tsang

Hong Kong J Radiol 2010;13(Suppl):S29-32

Glioblastoma multiforme is a highly invasive and aggressive brain tumour. It is the most commonly seen glioma with fast-growing features, being a devastating disease with no clear causation and no means of early detection. Less than 10% of glioblastoma

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W Yeo

Hong Kong J Radiol 2010;13(Suppl):S25-8

Gastric cancer is the fourth commonest cancer worldwide, with nearly a million new patients being diagnosed with this disease per year, of whom 55% are in East Asia. Regrettably, despite the availability of potentially curative resection, between 50 and 90% of

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E Tse, YL Kwong

Hong Kong J Radiol 2010;13(Suppl):S22-4

Malignant lymphoma is a common neoplasm and some are potentially curable if appropriate therapy is given. The use of the monoclonal anti-CD20 antibody rituximab in the management of follicular lymphoma has improved the outcome of patients.

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VHF Lee

Hong Kong J Radiol 2010;13(Suppl):S16-21

Systemic chemotherapy has been the standard treatment for advanced / metastatic non–small-cell lung cancer, particularly in those who do not harbour an epidermal growth factor receptor mutation. In the last decade, there was no established evidence to justify

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ML Zhuo, J Wang

Hong Kong J Radiol 2010;13(Suppl):S10-5

The epidermal growth factor receptor tyrosine kinase inhibitors, including gefitinib and erlotinib, have been proven to provide significant benefit in progression-free survival and overall survival in patients who have received at least one line of prior

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Hong Kong J Radiol 2010;13(Suppl):S3-9

J Cassidy

Colorectal cancer is one of the most frequently diagnosed malignancies in the world. In spite of recent advances in chemotherapy, the prognosis for patients with metastatic colorectal cancer remains poor. The last decade of ground-breaking research on molecular

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AKC Leung, KH Au, HY Yiu, YL Kwok, VC Sin, WL Leung, KC Ngan

Hong Kong J Radiol 2010;13:12-22

Objective: To study the clinico-pathological characteristics and outcome of germ cell tumours treated in the Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong.

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WSW Chan, SS Chiu, DHY Cho, SK Kei, WL Poon, SH Luk, CC Cheung

Hong Kong J Radiol 2010;13:3-11

Objective: This study evaluated the clinical, biochemical, and imaging characteristics to identify pre-ablative prognostic factors for the survival of patients undergoing radiofrequency ablation of hepatocellular carcinoma. Radiofrequency ablation has now been

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WK Cheung, KH Lee, HC Cheng, CH Cheung, CL Chan, KC Ngan

Hong Kong J Radiol 2010;13:125-32

Objective: RapidArc (Varian Medical Systems, Palo Alto, CA) is a new volumetric-modulated arc radiotherapy technique with continuous modulation of gantry speed, dose rate, and multileaf collimator shape. Taking advantages of dose painting capabilities

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BT Kung, CP Wong, KS Chu, TK AuYong, CM Tong

Hong Kong J Radiol 2010;13:120-4

Objectives: To determine the prevalence of focal thyroid fluorodeoxyglucose positron emission tomography– computed tomography incidentaloma in our locality and evaluate the rate of malignancy.

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SSM Lo, KY Kwok, CW Siu, WK Wong, CM Chan, KW Tang, YL Cheung, SCH Chan

Hong Kong J Radiol 2010;13:111-9

Objectives: Malignant spinal cord compression is an uncommon complication in patients with cancer. It is frequently diagnosed late and causes irreversible damage to spinal cord. Malignant spinal cord compression is an oncological emergency, requiring a prompt

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DD Rasalkar, BK Paunipagar, ABW Chan

Hong Kong J Radiol 2010;13:73-5

Heterotopic pancreas is the presence of pancreatic tissue outside the normal location lacking ductal or vascular continuity with the main gland. There are case series describing the computed tomographic appearance