Immunoglobulin G4–related Systemic Disease: Pictorial Review of the Pancreatic and Extrapancreatic Manifestations
LWY Chan, JHY Leung, CC Chan
Hong Kong J Radiol 2015;18:316-25
DOI: 10.12809/hkjr1414238
Immunoglobulin G4–related systemic disease (IgG4-RSD) is a newly recognised and emergent condition, which was initially thought to manifest only as autoimmune pancreatitis. As the knowledge about this disease grows, it is now known that it also manifests in various extrapancreatic organs. Some of the appearances can mimic neoplasms leading to unnecessary surgery and anxiety. This pictorial review presents the characteristic radiological features of IgG4-RSD in various organs with different imaging modalities. We hope to raise awareness of this new disease entity and assist the differentiation of lesions due to IgG4-RSD from other pathologies.
中文摘要
免疫球蛋白G4相關的系統性疾病：胰腺和胰腺外其他組織臨床表現的圖文回顧
陳慧儀、梁凱瑩、陳澤宗
免疫球蛋白G4相關的系統性疾病（IgG4-RSD）是一種新近提出並不斷發展的疾病，這種疾病最初認為僅表現為自身免疫性胰腺炎。伴隨對這種疾病的深入了解，目前認為IgG4-RSD也會涉及胰腺外的其他器官，其中一些表徵與腫瘤很相似，因而導致了不必要的手術及焦慮。本圖文回顧展示了IgG4-RSD在不同器官中影像學的不同特徵，希望借此提高人們對這種新疾病的認識，從而協助分辨IgG4-RSD及其他疾病。