Diagnosing Gout with Dual-energy Computed Tomography: Principles, Diagnostic Performance, and Clinical Application
JPK Tsang, MK Yuen
Hong Kong J Radiol 2017;20:98-102
DOI: 10.12809/hkjr1716838
Gout is an inflammatory response to deposition of monosodium urate (MSU) crystals in soft tissues and joints, and is the most common form of inflammatory arthritis in adults. Dual-energy computed tomography (CT) is a non-invasive tool for diagnosis, volume quantification of MSU crystals, and monitoring of treatment response. Dual-energy CT is included in the 2015 American College of Rheumatology / European League Against Rheumatism gout classification criteria. Although dual-energy CT has lower sensitivity when restricted to individual crystal-proven gouty joints in non-tophaceous disease, its diagnostic performance is good to excellent for tophaceous gout.
Authors’ affiliation:
JPK Tsang, MK Yuen: Department of Radiology, Tuen Mun Hospital, Tuen Mun, Hong Kong
中文摘要
雙能電腦斷層掃描診斷痛風：原理、診斷性能和臨床應用
曾佩琪、袁銘強
痛風是對軟組織和關節沉積尿酸鈉（MSU）的炎症反應，是成人中最常見的炎性關節炎形式。雙能電腦斷層掃描（CT）是非侵入性診斷工具並用於測量MSU結晶體積定量和監測治療反應。它被列入2015年美國風濕病學院／歐洲防風濕病聯盟痛風分類標準。雖然雙能CT在偵測個別結晶痛風關節的非痛風石疾病的靈敏度較低，但對痛風石有良好診斷性能。