Radiation Dosimetry in Selective Internal Radiation Treatment in Patients with Portosystemic Shunts to Umbilical Veins
WH Ma, S Ng, WY Ho, M Law, VHF Lee, KK Wong, WK Tso
Hong Kong J Radiol 2016;19:137-40
DOI: 10.12809/hkjr1615351
Tc-99m macroaggregate albumin (MAA) scintigraphy was routinely used to estimate the hepatopulmonary shunt prior to Yttrium-90 microsphere therapy. Visualisation of the recanalised umbilical vein / falciform artery in the breakthrough scan was not uncommon. Most centres believe that it is safe to proceed to selective internal radiation treatment with or without prophylactic embolisation based on clinical experience. This report aimed to calculate the patient-specific skin dosimetry based on the MAA single-photon emission computed tomography / computed tomography images and estimate the effect on skin after radioembolisation in patients with MAA uptake in recanalised umbilical vein.
中文摘要
接受選擇性體內放射治療患者從肝門脈系統分流至臍靜脈的輻射劑量
馬慧嫻、吳楚儀、何偉然、羅惠明、李浩勳、黃家建、曹偉權
鍀〔99mTc〕聚合白蛋白（MAA）顯像經常用於釔90微球治療前作為肝肺分流估計。掃描上觀察到的臍靜脈/鐮狀動脈的再管化並不少見。大多數治療中心認為根據臨床經驗，不論是否有預防性栓塞，進行選擇性體內放射治療都是安全的。本報告旨在根據MAA單光子發射電腦斷層/電腦斷層掃描圖像計算出特定病人的皮膚劑量，並估計在攝取了MAA臍靜脈再管化後的病人接受放射性栓塞後對皮膚的影響。