Potential Role of Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Immunoglobulin G4-related Systemic Disease
BT Kung, CP Wong, TK Au-yong, CM Tong
Hong Kong J Radiol 2013;16:230-4
DOI: 10.12809/hkjr1312138
We report on a 60-year-old man who presented with painless obstructive jaundice, suspicious of hilar cholangiocarcinoma. Positron emission tomography–computed tomography (PET-CT) demonstrated markedly fluorodeoxyglucose-avid bilateral enlarged submandibular masses and extensive hypermetabolic supra- and infra-diaphragmatic lymphadenopathy. Left submandibular excisional biopsy revealed immunoglobulin G4-related systemic disease. Compared with CT or magnetic resonance imaging, fluorine-18 fluorodeoxyglucose PET-CT not only allows whole-body imaging, but also offers metabolic information that helps to reflect disease activity. Fluorine-18 fluorodeoxyglucose PET-CT is a potential useful tool for diagnosis, treatment response assessment, and relapse detection of this systemic disease that is worth further exploration.
中文摘要
氟脫氧葡萄糖PET-CT在免疫球蛋白G4相關性系統性疾病中的潛在作用
龔本霆、黃治平、歐陽定勤、唐卓敏
本文報告一名60歲男子，病發時出現無痛性梗阻性黃疸，懷疑是肝門部膽管癌。正電子發射斷層掃描—電腦斷層掃描（PET—CT）顯示氟脫氧葡萄糖明顯濃聚的雙側下頜下腺增大的腫塊和橫膈上下方廣泛代謝增高的腫大淋巴結。左側下頜下腺切除活檢顯示免疫球蛋白G4相關性系統性疾病。與CT或磁共振相比，18氟脫氧葡萄糖PET—CT不僅可作全身顯像，而且還提供了代謝信息，有助反映病情活動。氟18氟脫氧葡萄糖PET—CT是一種潛在的有用工具，可用作該系統性疾病的診斷、治療反應評估和復發檢測，值得進一步探討。