Relapsed Hodgkin’s Lymphoma after Autologous Bone Marrow Transplant
CY Ha
Hong Kong J Radiol 2012;15(Suppl):S85-7
This report describes a 28-year-old woman with stage IV Hodgkin’s lymphoma with nodular sclerosis and bone marrow involvement. The patient received four cycles of adriamycin, bleomycin, vinblastine, and dacarbazine combination chemotherapy and achieved only partial response. Salvage therapy with cytarabine, cisplatin, and dexamethasone followed by autologous bone marrow transplantation improved control of the disease partially, but the patient ultimately had a relapse. Further options for salvage therapy in stage IV Hodgkin’s lymphoma are discussed, and the patient’s response to these therapies is described.
中文摘要
自體骨髓移植後出現復發性霍奇金淋巴瘤
夏頌賢
本文報告一名28歲女性，她患有第四期霍奇金淋巴瘤（結節硬化型）並有骨髓轉移。病人接受利 用adriamycin、bleomycin、vinblastine和dacarbazine的合併化療共四個療程，但只有部份緩解。使用 cytarabine、cisplatin和dexamethasone後再以自體骨髓移植的補救治療亦只改善部份病情，但病人最終 出現復發。本文會討論第四期霍奇金淋巴瘤的補救療法，以及研究病人對這些療法的反應。