Resolution of Pulmonary Metastases after Surgical Removal of Clear Cell Meningioma

A Dubey, HI Chalchal, M Salim, R Koul

Hong Kong J Radiol 2011;14:29-34

We report a rare instance of complete resolution of pulmonary metastatic lesions after gross total resection of a clear cell meningioma. This case showed that clear cell meningioma could metastasise to the lungs and that complete excision of the primary tumour resulted in resolution of the metastatic lesions, which is a phenomenon that has never been reported in the literature.

A 25-year-old man presented with clear cell meningioma involving right parasagittal area. After incomplete resection of the primary tumour, he developed multiple bilateral pulmonary metastases and the anaemia of chronic disease. The metastatic lesions were confirmed by open biopsy to be from the clear cell meningioma. Following complete excision of the primary brain lesion, all the pulmonary metastatic lesions underwent spontaneous resolution and the patient has been free of disease for the last five years. Systemic spread of the tumour and later spontaneous resolution of metastatic lesions after complete removal of the primary suggests that aggressive local control of primary lesions should be attempted whenever possible.

中文摘要

手術移除透明細胞型腦膜瘤後肺轉移癌的自動緩解

A Dubey、HI Chalchal、M Salim、R Koul

本文報告一宗完全切除透明細胞型腦膜瘤後肺轉移癌徹底緩解的罕見病例。這病例顯示透明細胞型腦膜瘤可向肺部轉移，原發腫瘤完全切除後會令轉移病變徹底消失。文獻中未有發表類似的病例報告。一名25歲男性的右矢狀竇旁發現透明細胞型腦膜瘤，他曾接受切割手術但未有把腫瘤完全切除，其後病人出現雙肺多發轉移癌和慢性貧血。病人切開活組織檢查確定轉移病灶來自透明細胞型腦膜瘤。其後把原發腦腫瘤完全切除後，發現其肺部轉移癌隨即自動消失。病人術後五年內未有復發。本病例腫瘤系統性轉移因切除原發腫瘤而誘發轉移癌自行消失，提示可能的話應盡量控制局部原發腫瘤。