Myelination Clock: a Simplified Step-by-step Approach to Normal Myelination

Full Article

SM Prabhu, V Yadav, D Prakash, S Sudhakar, S Mani

Hong Kong J Radiol 2016;19:208-16

DOI: 10.12809/hkjr1614286

Myelination is an essential step in the functional maturation of the brain. Magnetic resonance imaging allows the degree of maturation of a child’s brain to be assessed by estimation of the degree of myelination. Myelination follows an orderly and predictable sequence. Understanding the normal sequence and identifying an aberrant course can enable early detection of various leukodystrophies and hypomyelinating conditions. The purpose of this article was to describe a simple step-by-step approach that highlights important review areas and enables rapid and easy determination of the degree of myelination.

 

中文摘要

 

髓鞘的發展過程:觀察正常髓鞘形成的一個簡化步驟

SM Prabhu, V Yadav, D Prakash, S Sudhakar, S Mani

 

髓鞘化是大腦邁向成熟的重要步驟。MRI可以透過髓鞘形成的程度來評估兒童大腦的發展過程。髓鞘的形成是有序並可預測的一個過程。了解正常髓鞘化的過程以及辨識異常可及早發現各種腦白質營養不良和髓鞘過少的症狀。本文描述一個簡單的步驟來集中觀察一些重要區域,以及更快捷簡便地判定髓鞘化的程度。